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KMID : 0358819840110020153
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Journal of Korean Society of Plastic and Reconstructive Surgeons
1984 Volume.11 No. 2 p.153 ~ p.160
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EXPERIMENTAL STUDY ON THE EFFECT OF PREOPERATIVE ANGIOGRAPHY ON MICROVASCULAR ANASTOMOSIS
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Kim Woo-Kyung
Choi Eung-Ok
Chung Chun-Eun
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Abstract
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Preoperative angiography of donor and recipient vessels before free flap transfer is helpful in evaluation and planning the operation. However, use of this clinically useful method is still controversial because of the possible harmful effect on intima and thrombus formation.
We designed an experimental study on the effect of preoperative angiography on microvascular anastomosis.
Fifty Sprague-Dawley rats, weighing 250∼300gm, were divided into 5 groups.
Group 1: Normal saline injention with immediate anastomosis
Group 2: Contrast media injention without anastomosis
Group 3: Contrast media injection with immediate anastomosis
Group 4: Contrast media injection with 1wk. later anastomosis
Group 5: Contrast media injection with 2wk. later anastomosis
CONRAY was injected through abdominal aorta 1∼1.2ml respectively and femoral artery and vein were cut and reanastomosed under operating microscope. Four weeks later, reexploration was performed, and then patency rate and histologic change was observed.
The result was summerized as followings:
1) There were no statistically significant different patency rates between each group.
2) In all groups, it revealed patent vessel lumen without loss of endothelial layer. And there was no erythrocyte aggregation, no platelet adhesion.
With this findings, we can conclude that there was no significant harmful effect of preoperative angiography on microvascular anastomosis.
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KEYWORD
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